Stroke: in the US, new drug repairs brain damage


The University of Cincinnati certifies a new drug capable of repairing the damage caused by stroke . The drug has the name of NVG-291-R and has led to the repair of the nervous system with related functional recovery. All experimented on a guinea pig affected by a severe stroke.


Most of today’s therapies focus primarily on reducing the early damage of stroke. However, our group has focused on neuroreparation as an alternative and has now shown that treatment with NVG-291-R not only results in neuroprotection to reduce neuronal death, but also in robust neuroreparative effects. The only drug currently approved by the FDA for the treatment of stroke does not repair the damage and must be given within 4.5 hours of starting the stroke. Most of the therapies being researched must be applied within 24-48 hours of starting a stroke. A product that works to repair stroke damage, even a week after the onset of symptoms, would change the paradigm for stroke treatment.

Agnes (Yu) Luo, associate professor at the University of Cincinnati and senior author of the study

It was found that this drug is still effective even after one week after the stroke . A lecturer and study co-author, Jerry Silver, testified that the drug repaired the damage. He made new neuronal connections and improved the path of neurons in the direction of the damaged area.


This strong plasticity is excellent confirmation of the same powerful mechanisms that we and other researchers have been able to demonstrate using NVG-291-R in spinal cord injury.

Jerry Silver, lecturer and co-author of the study

The pharmaceutical company that holds the worldwide rights to the new drug is NervGen Pharma. The brand supports research on the self-healing functions of the nervous system. Meanwhile, the drug is being tested on healthy individuals. In the future, the new drug will also launch application tests on patients with spinal cord injury, multiple sclerosis and Alzheimer’s disease.

  • Stroke, tested a new drug that repairs the damage (


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